The advent of CRISPR & genome editing technologies has ushered in a new era of genetic precision, enabling targeted modifications with unprecedented accuracy. CRISPR-Cas systems allow scientists to cut, delete, or replace DNA sequences in a wide range of organisms, offering therapeutic possibilities for genetic diseases, cancer, and infectious conditions. Beyond CRISPR, novel editing tools like base editors and prime editors are expanding the genome editing toolkit. Researchers are now combining CRISPR & Genome Editing Technologies with delivery platforms such as viral vectors and nanoparticles to improve efficiency and specificity. These tools are also critical for functional genomics, crop enhancement, and synthetic biology. As ethical and regulatory frameworks evolve, genome editing remains one of the most transformative technologies in modern biotechnology.