Dr. Castellino studied Chemistry as an undergraduate at the University of Scranton (PA) and graduated with a BS in 1964. He then was a graduate student in Biochemistry at the University of Iowa with Robert Barker, where he graduated with a M.S. and PhD. In 1968. Following this, he was a postdoctoral fellow at Duke University with Robert L Hill. Dr. Castellino joined the Department of Chemistry and Biochemistry at the University of Notre Dame in 1970, where he remained to this day. He is currently the Kleiderer-Pezold Professor of Biochemistry.