Gene editing technologies enable precise modifications to DNA sequences within cells, revolutionizing biomedical research and therapeutic approaches. CRISPR-Cas9, the most prominent method, uses RNA-guided enzymes to target specific genetic sequences and induce alterations like gene knockout, correction of mutations, or regulation of gene expression. Other tools include TALENs (Transcription Activator-Like Effector Nucleases) and zinc finger nucleases, each with unique strengths in accuracy and efficiency. Applications span basic research to treat genetic disorders, cancer, and infectious diseases. Ongoing research focuses on refining delivery methods, enhancing specificity, and addressing ethical considerations for safe and effective clinical implementation of gene editing technologies.
Tracks:
CRISPR-Cas Systems
Delivery Methods
Off-Target Effects and Specificity
Clinical Applications
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