Biomarkers of cancer stem cells (CSCs) are molecular or cellular characteristics that distinguish CSCs
from other tumor cells. These biomarkers aid in identifying, isolating, and studying CSCs, which are
crucial for understanding their role in cancer initiation, progression, and treatment resistance.
Common CSC biomarkers include surface proteins (e.g., CD44, CD133), transcription factors (e.g., Sox2, Oct4), and signaling pathways (e.g., Notch, Wnt). Biomarkers help in predicting patient prognosis, monitoring treatment responses, and developing targeted therapies that specifically target CSCs to prevent tumor relapse and metastasis. Research into CSC biomarkers continues to advance precision medicine approaches in oncology.
Tracks:
Identification and Characterization
Functional Validation
Clinical Relevance
Therapeutic Targeting